Wednesday 30 November 2011

HEPATITIS B

How to Hurt Liver Hepatitis B Virus

How ill If There's Disease in the Human Body. How ill, if you have Hepatitis B. Activity we would be distracted and uncomfortable. Hepatitis B virus itself does not directly cause damage to the liver. Presumably, the body's immune response against the virus causing damage. So, in a hepatitis B virus infection, the body's immune response to the virus bertanggunga responsible for both, elimination (elimination) of hepatitis B virus from the body and healing of the infection. However, at the same time, injury to liver cells caused by the same immune response to hepatitis B virus in liver cells. if this sick, really ill.

Therefore, there is a balance between protecting effects and that destroy the immune system response to viral hepatitis B. How this balance is achieved determines the final outcome on an individual infected with viral hepatitis. Hence, an acute viral infection with hepatitis B can lead to healing (common outcome), in acute liver failure (rare), and occasionally in chronic infection. Chronic infection can result in a state of people with healthy (healthy carrier, which contains a virus affected people but still healthy) or proceed to cirrhosis (severe scarring, or fibrosis of the liver) and its complications, including liver cancer.

Deployment / Transmission of Hepatitis B

Hepatitis B virus is spread or acquired through exposure to infected blood or body expenditures. Concentrations of hepatitis B virus the highest found in the blood, semen, vaginal discharge, breast milk, and saliva. There are only concentrations of low hepatitis B virus in the urine and not in the stool. Therefore, hepatitis B is not spread through food or drink or casual contact. Furthermore, the hepatitis B virus no longer infected by blood transfusions because all blood for transfusion is screened (inspected) to eliminate the pollution or contamination with viral hepatitis B.

In America, young adults and responsible for many cases of hepatitis B infection were reported. Sexual contact are the ways of transmission of the most common. Viruses can also be transmitted by blood or body fluids contaminated with the hepatitis B virus in several different ways. These methods include intravenous drug use, skin-popping (subcutaneous injections), tattoos, menindi body, and acupuncture use the tools that are not sterile. In addition, hepatitis B virus can be infected through shared use of toothbrushes and shaving equipment. Finally, blood-sucking insects such as mosquitoes and fleas tropical bed has been reported to transmit hepatitis B virus.

Last (but not the most recent), hepatitis B virus can be transmitted from infected mothers to their babies at birth (the so-called vertical transmission). These are the ways of transmission of the most important in areas where hepatitis B virus infection is always present (endemic), such as in Southeast Asia and Sub-Saharan Africa. Rate of transmission of hepatitis B virus to babies born to mothers who are severely infected is very high, approaching 100%. Moreover, as indicated earlier, almost all of these infants will develop chronic hepatitis B virus infection.

Symptoms of Hepatitis B

Specifically terserangnya signs and symptoms of acute hepatitis B are fever, abdominal pain and yellow (especially in the area of ​​the white eye / sclera). But for people with chronic hepatitis B will tend not to appear the signs, so that transmission to others becomes more risky.

Handling and Treatment of Hepatitis B

Patients with suspected Hepatitis B, for the certainty of diagnosis that is established then it will be blood examination. Once the diagnosis is established as Hepatitis B, then there is a treatment for hepatitis B, namely treatments swallowed (oral) and by injection.

a. Oral treatment is the famous;

- Provision of drugs from the nucleoside analog Lamivudine, which is known as 3TC. This medicine is used for adults and children, drug use tends to increase liver enzyme (ALT) for that patient will receive ongoing monitoring of doctor.

- Provision of drug adefovir dipivoxil (Hepsera). Oral administration would be more effective, but administration with high doses would adversely affect renal function.

- Provision of drug Baraclude (Entecavir). The drug is administered in patients with chronic hepatitis B, the side effects of this drug are headache, dizziness, fatigue, nausea and an increase in liver enzyme. Keoptimalan level and stability of drug administration has not said to be stable.

b. Treatment with injection / injection is;

Microsphere injections containing ß-ray-emitting radioactive particles that will destroy liver cancer cells without damaging surrounding healthy tissue. Interferon Alfa Injection (by branch name INTRON A, INFERGEN, ROFERON) subcutan given the scale of 3 times a week for 12-16 weeks or more. Side effects of this drug are depression, especially in patients that have a history of previous depression. Another effect is a pain in the muscles, causing fatigue and a little fever that this can be eliminated by administering paracetamol.

Preventive measures to avoid the disease is Hepatitis B vaccine delivery, especially in people at high risk of this virus, such as those who behave bad sex (change-change partner / homosexuals), health workers (nurses and doctors) and their areas that are vulnerable many cases of Hepatitis B.



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